Pacing in tachycardia
HIS synchronous VPB / Zipes
What is ZIpes?
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Zipes involves adding a paced VPB during tachycardia when the HIS is refractory.
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This means that it is impossible for the VPB to have retrograde conduction up the AV node due to refractoriness.
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If there is any change is the following A-A interval this demonstrated an extra circuit is present in the heart (accessory pathway)

How to perform
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Sensed extra with Ventricular stimulus faster rate than TCL
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Cease when tachy terminates or V appears to be HIS synchronous
Confirming beat is HIS synchronous
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Ensure ventricular capture
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Measure H-H interval on beat prior to paced beat
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Drag caliper onset to His – prior to stimulus and lock in
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Measure how early pacing artefact is compared to caliper offset
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See if there is any effect in timing for the following atrial event





Responses to Zipes
No change in A-A
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consistent with AVNRT
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AVRT is not ruled out
​
Tachycardia termination with no A
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active AVRT pathway
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Delay in A-A interval
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active decremental AVRT pathway
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A-A advancement
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could be an active pathway or
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a bystander pathway
*ventricular advancement/delay proves active pathway
​
Ventricular entrainment
How to perform
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Paced 20-30ms faster than TCL in the ventricle until ~10 capture beats
-Pacing for too long or too fast may terminate tachycardia
-Pacing too slow will not capture the ventricle
Confirming entrainment
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Ensure there is ventricular capture
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Ensure the same tachycardia continues when coming off pacing
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Measure A-A interval on the last few beats to ensure A is entrained
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View response immediately after
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Measure the 1st return atrial event to ensure there is no pseudo VAAV response
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Measure PPI-TCL by measuring stimulus artefact to return signal on paced catheter
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Measure Stim-A – VA by measuring stimulus-entrained A & compare to tachycardia VA
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Look at the start of the entrainment and choose the 1st fully capture ventricular event
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Measure forward the A-A intervals until you see a AA interval that equals the ventricular entrainment rate







Responses to Entrainment
Immediate response
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VAV: nodal involvement (AVRT/AVNRT)
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VAAV: atrial tachycardia (ensure is not pseudo VAAV)
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Post pacing interval - tachcardia cylce length (PPI-TCL)
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>115ms AVNRT
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<115ms septal pathway
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Stim A interval - VA interval
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>85ms AVNRT
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<85ms AVRT
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Number of beats to entrain the atrium
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1 AVRT
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>1 AVNRT
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Late & Early APBs
How to perform
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Sensed extra with Atrial stimulus faster rate than TCL
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Cease when tachy terminates, A appears to be HIS synchronous or risk of AF
Confirming late APBs
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Confirm there is atrial capture
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Measure H-H / V-V interval on beat prior to paced beat
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Ensure the immediate beat is not effected
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Measure the following H-H / V-V to see if there is any change in interval compared to the TCL
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If there is a change in VV, measure the VA interval and compare to Tc VA





Confirming early APBs
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Confirm there is atrial capture
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Measure H-H interval on beat prior to paced beat
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Ensure the immediate beat is effected
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Observe the response after
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If tach continues, compare immediate VA to Tc VA




Responses to APBs
Late APB
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HV advanced
-consistent with AVNRT (if unchanged VA)​
-consistent with atrial tachycardia (if VA is unlinked)
-could still be junctional tc if slow pathway is present (not rules out)
​
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HV delayed
-consistent with AVNRT (linked VA)​
consistent with atrial tachycardia (unlinked VA)
​
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Tachycardia terminated
-consistent with AVNRT
​
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No change
-consistent with junctional tachycardia​
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Early APB
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Tachycardia continues​
-consistent with junctional tachycardia​
-consistent with atrial tachycardia (if VA is not linked)
​
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Tachycardia terminates
-consistent with AVNRT
(fast pathway interrupted for short VA tc, slow pathway interrupted for long VA tc)​
Atrial entrainment
How to perform
-
Paced 20-30ms faster than TCL in the atrium until ~10 capture beats
-Pacing for too long or too fast may terminate tachycardia
-Pacing too slow will not capture the atrium
Confirming entrainment
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Ensure there is atrial capture
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Ensure the same tachycardia continues when coming off pacing
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Measure V-V interval on the last few beats to ensure V is entrained
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View the morphology of the entrained V beats
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View response immediately after





Responses to atrial entrainment
SVT
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AVA response
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No change in ventricular morphology
​
VT
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AVVA​​
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change in ventricular morphology